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Tesamorelin

Tesamorelin (Egrifta)

Strong RCTFDA Approved

An FDA-approved GHRH analog originally for HIV-related lipodystrophy, now widely used for visceral fat reduction and body composition.

Mechanism of action

GHRH receptor agonism, GH stimulation, visceral fat reduction, IGF-1 elevation

Primary benefits

  • Visceral fat reduction
  • Lean muscle preservation
  • Improved body composition
  • Cognitive benefits
  • GH restoration

Dosing

Beginner
1 mg/day
Intermediate
1-2 mg/day
Advanced
2 mg/day
Frequency: Once daily
Timing: Pre-sleep fasted
Route: Subcutaneous injection

Cycling protocol

Duration
12-26 weeks
Pattern
Daily
Break after
4-8 weeks

Important warnings

  • ⚠️FDA-approved for HIV lipodystrophy — off-label for general use
  • ⚠️Prescription required
  • ⚠️Monitor glucose levels

Stacks well with